Read number effect

Here shows analysis of sample size effect

figure of down-sampling effect

Samples

The following three metagenomic data were used for analysis.

・Hot spling [DRR163688]: reported temperature is 96.8°C

・Human gut [DRR127552]

・Soil (main fire)[SRR7882662]: reported temperature is 57.4°C

Subsampling

Arbitrary number of reads were subsampled by 30 replicates using Seqkit.

Graph summarized the MPT predicted from each subsamples.

Conclusion

When the read number is more than 100,000, standard deviation of the predicted value can be suppressed to 0.5°C or less in various environmental data.